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Mohite, V. T.
- Effects of Sub-Lethal Dose of Nickel on the Biochemical Parameters in the Tissues of Female Crab Scylla serrata, from Mumbai Coast
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Authors
Affiliations
1 Department of Zoology, Thakur College of Science and Commerce, Kandivli (E), Mumbai, IN
2 Department of Environmental Science, Shivaji University, Kolhapur, IN
1 Department of Zoology, Thakur College of Science and Commerce, Kandivli (E), Mumbai, IN
2 Department of Environmental Science, Shivaji University, Kolhapur, IN
Source
Journal of Ecophysiology and Occupational Health, Vol 12, No 1-2 (2012), Pagination: 69-76Abstract
The effects of sub-lethal concentration of nickel on the biochemical composition such as glycogen, protein, cholesterol, lactic acid, pyruvic acid in gills, hepatopancreas, muscles and sugar contents along with haemolymph in female crab, Scylla serrata procured form local fish market in Mumbai (Sassoon Dock) were studied. The female crabs were exposed to sub-lethal dose of nickel LC and LC were 200ppm and 500ppm 0 50 respectively. Among the control set the glycogen contents were found to be the highest in muscles (44.616±0.225 mg/gm wt); protein contents were maximum in gills (66.5232±0.170 mf/gm wt); cholesterol contents were highest in ovary (2.009±0.006 mg/gm wt). The sub-lethal dose of nickel caused decline in the contents of glycogen (1.030±0.0141), protein (11.299±0.055), cholesterol (1.373±0.008) and pyruvic acid (0.440±0.195) in most of the tissues studied. The lactic acid contents increased in all the tissues studied in response to the exposure of nickel. The sugar and lactic acid contents in haemolymph were elevated as a result of exposure whereas the contents of protein, cholesterol and pyruvic acid in haemolymph declined due to the sub-lethal exposure in female crabs.Keywords
Scylla Serrata, Nickel, Glycogen, Protein, Cholesterol, Lactic Acid, Pyruvic Acid.- Study on the Effects of Exposure of Sub Lethal Dose of Cadmium and Zinc on the Enzymatic Activity in the Tissues of Green Mussel-Perna viridis (L.) from Ratnagiri Coast, Maharashtra
Abstract Views :273 |
PDF Views:131
Authors
Affiliations
1 Department of Zoology, Thakur College of Science and Commerce, Kandivli (E), Mumbai 400101, IN
1 Department of Zoology, Thakur College of Science and Commerce, Kandivli (E), Mumbai 400101, IN
Source
Journal of Ecophysiology and Occupational Health, Vol 11, No 3-4 (2011), Pagination: 131-140Abstract
This research paper reports on the effects of exposure of green mussel to sub lethal concentrations of cadmium and zinc on GOT, GPT, ACP and ALP activities in the tissues of mantle, gill, hepatopancreas, adductor muscle, siphon, foot and gonad of Perna viridis. Exposure of sub lethal concentration of cadmium for 15 days resulted in the increase of GOT activity in all the tissues and was found to be the maximum in mantle and gonad but declined in hepatopancreas, siphon and foot. 30 days exposure of cadmium caused over all increase in GOT activity but the maximum was found to be in gonad although hepatopancreas and mantle showed higher levels of this activity. The GOT activity increased in all the tissues except in adductor muscle and the maximum in hepatopancreas and gonad as a result of exposure to lower concentration of zinc. Higher concentration of zinc for 30 days resulted in the increase in the activity in all the tissues but being higher in hepatopancreas, gill and gonad. GPT activity due to exposure to lower concentration of cadmium declined in mantle, adductor muscle, siphon, gill and gonad but it showed gentle rise in case of hepatopancreas and foot after 30 days of exposure. The exposure of lower concentration of zinc caused decline in GPT activity in mantle, adductor muscle, siphon, foot and gonad while in gill it increased. The ACP activity increased in all the tissues except in adductor and gonad during 15 days exposure to cadmium while exposure to zinc brought about elevation in all the tissues except gill. The exposure for 30 days resulted in decline in ACP activity in hepatopancreas, mantle and foot. 15 days exposure to cadmium enhanced the ALP activity in all the tissues but not in foot where as 30 days exposure resulted in decline in ALP activity in mantle, gill and adductor muscle. Exposure of zinc caused gradual increase in ALP activity in all the tissues studied. Thus, there is a possibility that Perna viridis can act as an indicator of pollutant contamination due to cadmium and zinc.Keywords
Green Mussel, Cadmium, Zinc, GOT, GPT, ACP, ALP.- Effect of Anticancer Drug Etoposide (VP-16) on Reproductive Organs of Male White Rat
Abstract Views :277 |
PDF Views:121
Authors
M. A. Mhatre
1,
V. T. Mohite
2
Affiliations
1 Department of Zoology, C.K. Thakur A.C.S. College, New Panvel, Navi Mumbai – 402107, IN
2 Department of Zoology, Thakur College of Science and Commerce, Kandivali (E), Mumbai - 400 101, IN
1 Department of Zoology, C.K. Thakur A.C.S. College, New Panvel, Navi Mumbai – 402107, IN
2 Department of Zoology, Thakur College of Science and Commerce, Kandivali (E), Mumbai - 400 101, IN
Source
Journal of Ecophysiology and Occupational Health, Vol 15, No 3-4 (2015), Pagination: 115-119Abstract
The etoposide (VP-16) is in use as one of the regimen in cyclical chemotherapeutic treatment for several kind of cancer like testicular cancer, small cell bronchogenic carcinoma, malignant lymphoma. Etoposide (VP-16), an anticancer drug, 1mg/kg/day was administered intramuscular for two months. The animals were anaesthetized with ether and excised testis and epididymis for electron microscopic studies. The testicular tissue revealed that the severe atrophic changes, suggestive arrest at the germinal cell level as well as at the Sertoli cell level. The cellular integrity of all is drastically reduced with a severe nuclear alteration also taking place. The observations showed that damage of early spermatogonia and the later stages of spermatogenesis were completely eliminated. The leydig cells revealed state of work induced hypertrophy as is evident from the secretory activity but the organelles show a condition of extreme overburdened state just prior to state of collapse. In conclusion our result shows that adverse effect of etoposide on testis especially on spermatogonia can be distinguished after two months treatment. The electron microscopic features show that it leads towards the male fertility disorder.Keywords
Testis, Spermatogonia, Sertoli Cell, Leydig Cell, Epididymis, Principle Cell.References
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- Effect of Anticancer Drug Etoposide (VP-16) on Epididymis of Male White Rat
Abstract Views :287 |
PDF Views:156
Authors
M. A. Mhatre
1,
V. T. Mohite
2
Affiliations
1 Department of Zoology, C.K. Thakur A.C.S. College, New Panvel, Navi Mumbai – 402107, IN
2 Department of Zoology, Thakur College of Science and Commerce, Kandivali (E), Mumbai - 400 101, IN
1 Department of Zoology, C.K. Thakur A.C.S. College, New Panvel, Navi Mumbai – 402107, IN
2 Department of Zoology, Thakur College of Science and Commerce, Kandivali (E), Mumbai - 400 101, IN